Pall UF/DF Tangential Flow Filtration System

Pall UF/DF

This listing is for a Pall UF/DF Tangential Flow Filtration System.

The unit is in excellent working condition and is ready for immediate release.

The Pall UF/DF System is a state-of-the-art tangential flow filtration (TFF) skid designed for ultrafiltration and diafiltration (UF/DF) processes in biopharmaceutical manufacturing. This advanced stainless steel unit enables efficient concentration and buffer exchange of biologics such as monoclonal antibodies, recombinant proteins, enzymes, and gene therapy vectors.

Engineered by Pall Biotech and manufactured in Germany, this system ensures process reliability, hygiene, and scalability, meeting the rigorous demands of regulated production environments.

Ideal for downstream processing in pilot or GMP production, this system features a user-friendly HMI interface, robust control panel, and a fully integrated filtration circuit compatible with single-use or reusable membranes.

Key Features

GMP-Ready Design – Engineered to support pharmaceutical-grade UF/DF processes.

Integrated Touchscreen HMI – For real-time control and monitoring of process parameters.

Compact Stainless Steel Skid – Easy to manoeuvre and install in classified cleanroom environments.

Automated Operation – Equipped with an intelligent PLC for pressure, flow, and temperature control.

Multi-Function System – Supports both ultrafiltration and diafiltration processes.

High Purity Tubing & Fittings – Configured with sanitary connections and single-use flexibility.

Validated Safety Features – Includes emergency stop button, regulated pressure alarms, and lockable panels.

Technical Specifications

Parameter Details

Manufacturer Pall Biotech (Germany)

Year of Manufacture 2022

System Type UF/DF Skid (Ultrafiltration/Diafiltration)

Max Allowable Pressure 4 bar (58 psi)

Max Operating Temperature 80°C

Min Operating Temperature 5°C

Control System Touchscreen HMI with integrated PLC

Construction 316L Stainless Steel

Wheels Lockable castors for mobility

CE Marking Yes (Compliant with EU standards)

Serial Number

Applications

Biopharmaceutical Manufacturing – Concentration and buffer exchange for drug substances.

Monoclonal Antibody Purification – Clarification and polishing prior to formulation.

Gene Therapy & Vaccines – Processing of viral vectors, plasmid DNA, and mRNA.

Enzyme and Protein Products – Downstream UF/DF concentration steps.

Cell Culture Harvesting – Clarification of lysates and spent media.

Formulation – Final buffer exchange before sterile filtration and fill/finish.
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Benefits

Scalable Solution – Suitable for pilot-scale and full production batches.

Reliable Filtration – Maintains membrane integrity and product quality.

Process Efficiency – Fast changeover with user-friendly operation.

High Product Recovery – Designed to minimize hold-up volume and product loss.

Validated Platform – Developed by Pall, a global leader in bioprocessing technology.